Page 89 - Livre électronique du congrès national de pneumologie 2022

RESULTS : CONCLUSION :
We included 69 patients among which (59 men Our study shows the negative impact the SARS2
(85.5%) and 10 women (14.5%)) ; with a mean age of COVID Pandemic on the Tuberculosis management
(42 years) and a sex-ratio of (5.9).Then ,we divided in our high-endemic countries with worse outcomes
them in 2 groups according to the outbreak of the and more complications. We do underline the
COVID Pandemic : (G1 :35 patients (29 men (82.9%),6 efficiency of the TBC control strategies in our
women (17.1%)) ;G2 : 34 patients (30 men (88.2%),4 country. Further studies are required to highlight the
women (11.8%)) ; with a mean age of (39) years in G1 vs interaction between these two endemic diseases.
(45) years in G2 (p=0.219).
P65. DOES GENDER DIFFERENCE SERVE AS A
As regards with the lifestyle, the smoking rate was
about (75.4%). Job exposure was reported in (31.9%). BIOMARKER OF SEVERITY OF THE SARS-2 COVID
Besides, (36.2%) have received the SARS2 COVID INFECTION ?
vaccine ; with a full dose in (34.8%).
SAIDANE A, Daboussi S, Mhamdi S, Bahri K, Mejri I, Aichaouia
Tuberculosis was pulmonary in (52 cases) (89.7%), C, Moatameri Z, Khadhraoui M
pleural in (4 cases) (6.9%), ganglionar in (1 case) (1.7%)
and peritoneal in (1 case) (1.7%) in our study group. SERVICE DE PNEUMOLOGIE, HOPITAL MILITAIRE PRINCIPAL
D'INSTRUCTION DE TUNIS
Besides, the BK bacilli was isolated in the sputum in
(42 cases) (63.6%), bronchial liquid in (7 cases) (10.6%),
PCR sample (5 cases) (7.6%) and thanks to a pleural INTRODUCTION :
biopsy in (10 cases) (15.2%) . After the outbreak of the new Pandemic of COVID 19,

We noticed that the radiological lesions were more the trend is to seek for a Gender-disaggragated
extended in G2 (19 cases (55.9%) vs (6 cases (17.1%) in data, to understand the biology of the disease and
G1 (p=0.001). The mean delay of the TBC treatment assess the appropriate treatment.
onset was not different between both groups Gender Differences are likely due to a Behavioural
(p=0.887). However, the complications were more ,Genetic and Hormonal gap between them ,as well
common among the second group ((9 cases (26.5%) as distinct biological pathways related to SRAS2 –
vs (2 cases (5.7%) (p=0.021). In fact, the patients COVID virus. Some studies have suggested worse
included in G2 presented more bronchial dilation (1 outcomes among men affected with COVID.
cases (2.9%) vs 0 cases in G1 (p=0.321) ; more pleural However,the results remain controversial between
thickening ((8 cases (23.5%) in G2 vs (3 cases (8.6%) in countries.
G1 (p=0.065) and more TBC recurrence (1 cases (2.9%)
in G2 vs 0 cases in G1 (p=0.321). AIM OF THE WORK :
During the follow-up, TBC treatment interruption was We aimed to elucidate the impact of Gender
more common among the patients of the G2 (29.4% difference on the severity of the disesase.
vs 17.1%) (p=0.231). The main reasons of treatment METHODS :
interruption reported in our study group were :
Treatment toxicity (14.3% in G2 vs 5.9% in G1), 143 patients affected with COVID, admitted in our
problem of access to medical care (2.9% in G1), hospital ,from September 2020 to January 2021 ,were
SARS2 COVID Pandemic lockdown (2.9% in G2) included.Each patient was subjected to clinical
(2.9% in G2) (2.9% in G2) and lack of motivation (2.9% examination,blood samples,RNA-PCR sampling,an
in G2). electrocardiogram and a CT-Chest-Scan.

Concerning the outcomes, we have noticed more We assessed the clinical, biological and
deaths (2.9% in G2 vs 0 cases in G1(p=0.321)) and more radiological findings during the follow-up.
lost of view patients (20.6% in G2 vs 5.7% (p=0.075) in
G1) after the SARS2 COVID Pandemic among the TBC
infected patients.

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